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LDN-193188

LDN-193188 is a Phosphatidylcholine transfer protein (PC-TP) inhibitor. LDN-193188 regulates hepatic glucose metabolism, and can be used for study of glucose metabolism[1].

Product Specifications

CAS Number

[1267610-30-9]

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ldn-193188.html

Purity

99.69

Solubility

DMSO : 4.17 mg/mL (ultrasonic)

Smiles

O=C(NC(NC1=CC=C(S(=O)(NC2=NC(C)=CC(C)=N2)=O)C=C1)=O)C3=CC=C(Cl)C=C3Cl

Molecular Formula

C20H17Cl2N5O4S

Molecular Weight

494.35

References & Citations

[1]Shishova EY, et al. Genetic ablation or chemical inhibition of phosphatidylcholine transfer protein attenuates diet-induced hepatic glucose production. Hepatology. 2011;54 (2) :664-674.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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