Cbl-b-IN-5
Cbl-b-IN-5 (compound 6) is a Cbl-b inhibitor (IC50=3-10 µM) . Cbl-b-IN-5 has the potential to be used in the study of cancer and related diseases amenable to immune system modulation[1].
Product Specifications
CAS Number
[2368835-59-8]
UNSPSC
12352005
Target
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cbl-b-in-5.html
Purity
99.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(C1=CC(NC(C2=NC=CC=C2)=O)=CC=C1)SC3=NN=CN3C
Molecular Formula
C17H17N5OS
Molecular Weight
339.41
References & Citations
[1]Paul A. Barsanti, et al. Inhibitors of cbl-b and methods of use thereof. Patent WO2019148005A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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