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N-Desethyl amodiaquine dihydrochloride (Standard)

Selected Variant

HY-128554AR-01

Size: 1 mg

N-Desethyl amodiaquine dihydrochloride (Standard) is the analytical standard of N-Desethyl amodiaquine dihydrochloride. This product is intended for research and analytical applications. N-Desethyl amodiaquine dihydrochloride is the biologically active metabolite of Amodiaquine. N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC50 values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine dihydrochloride can be used for the research of malaria[1][2].

Product Specifications

CAS Number

79049-30-2

UNSPSC

12352005

Target

Parasite; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/n-desethyl-amodiaquine-dihydrochloride-standard.html

Smiles

OC1=CC=C(NC2=CC=NC3=CC(Cl)=CC=C23)C=C1CNCC.Cl.Cl

Molecular Formula

C18H20Cl3N3O

Molecular Weight

400.73

References & Citations

[1]Sasi P, et al. In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. J Infect Dis. 2009 Jun 1;199 (11) :1575-82.|[2]Xue-Qing Li, et al. Amodiaquine clearance and its metabolism to N-desethylamodiaquine is mediated by CYP2C8: a new high affinity and turnover enzyme-specific probe substrate. J Pharmacol Exp Ther. 2002 Feb;300 (2) :399-407.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Price

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