Amitifadine (hydrochloride)
Amitifadine (DOV-21947; EB-1010) hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI), with IC50s of 12, 23, 96 nM for serotonin, norepinephrine and dopamine in HEK 293 cells , respectively.
Product Specifications
CAS Number
410074-74-7
Product Name Alternative
DOV-21947 hydrochloride; EB-1010 hydrochloride
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Transporter; Serotonin Transporter
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Infection; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Amitifadine-hydrochloride.html
Purity
99.64
Solubility
DMSO : ≥ 100 mg/mL|H2O : 50 mg/mL (ultrasonic)
Smiles
ClC(C=C1[C@]2(CNC3)[C@@H]3C2)=C(C=C1)Cl.[H]Cl
Molecular Formula
C11H12Cl3N
Molecular Weight
264.58
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
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