Rbin-1
Rbin-1 is a potent, reversible, and specific chemical inhibitor of eukaryotic ribosome biogenesis. Rbin-1 inhibits the ATPase with GI50 of 136 nM. Rbin-1 is a potent and selective chemical inhibitor of Midasin (Mdn1) .
Product Specifications
CAS Number
[328023-11-6]
Product Name Alternative
Ribozinoindole-1
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Rbin-1.html
Purity
99.85
Solubility
DMSO : ≥ 31 mg/mL
Smiles
C=C(C)CSC1=NN=C2C(NC3=C2C=CC=C3)=N1
Molecular Formula
C13H12N4S
Molecular Weight
256.33
Precautions
H315, H319, H320
References & Citations
[1]Kawashima SA, et al. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Cell. 2016 Oct 6;167 (2) :512-524.e14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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