Tripelennamine (hydrochloride)
Product Specifications
UNSPSC Description
Tripelennamine hydrochloride, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine hydrochloride lessens the allergic response of the organism caused by histamine. Tripelennamine hydrochloride can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions[1][2][3].
Target Antigen
Endogenous Metabolite; Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Immunology/Inflammation;Metabolic Enzyme/Protease;Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/Tripelennamine-hydrochloride.html
Solubility
DMSO : 25 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Smiles
CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2.[H]Cl
Molecular Weight
291.82
References & Citations
[1]Manohar M, et al. H1-receptor antagonist, tripelennamine, does not affect arterial hypoxemia in exercising Thoroughbreds. J Appl Physiol. 2002 Apr;92(4):1515-23.|[2]Wasfi IA, et al. Comparative disposition of tripelennamine in horses and camels after intravenous administration. J Vet Pharmacol Ther. 2000 Jun;23(3):145-52.|[3]Yeh SY, et al. The pharmacokinetics of pentazocine and tripelennamine. Clin Pharmacol Ther. 1986 Jun;39(6):669-76.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-17428/Tripelennamine-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-17428/Tripelennamine-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
154-69-8
Available Sizes
Curated Selection
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