5,7-Dihydroxycoumarin
5,7-Dihydroxycoumarin is a coumarin isolated from the inflorescences of Macaranga triloba. 5,7-dihydroxycoumarin displays antibacterial characteristics with an MIC value in the range of 1000 mg/mL to >1000 mg/mL. Some 5,7-dihydroxycoumarin derivatives have antioxidant properties[1][2][3].
Product Specifications
CAS Number
[2732-18-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H332, H335
Target
Bacterial
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/5-7-dihydroxycoumarin.html
Purity
99.47
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C=CC2=C(C=C(C=C2O)O)O1
Molecular Formula
C9H6O4
Molecular Weight
178.14
Precautions
H302, H315, H319, H332, H335
References & Citations
[1]Ishak Zakaria, et al. Flavonoids with antiplasmodial and cytotoxic activities of Macaranga triloba. Fitoterapia. 2012 Jul;83 (5) :968-72.|[2]Yi-Ping Chin, et al. Synthesis and evaluation of antibacterial activities of 5,7-dihydroxycoumarin derivatives. Arch Pharm (Weinheim) . 2011 Jun;344 (6) :386-93.|[3]Lin M H, et al. Antioxidant properties of 5, 7-dihydroxycoumarin derivatives in in vitro cell-free and cell-containing systems. Journal of Experimental & Clinical Medicine, 2011, 3 (3) : 126-131.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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