Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Valiglurax

Valiglurax (VU0652957) is a potent, orally active and selective mGlu4 positive allosteric modulator with EC50 values of 64.6 nM and 197 nM for hmGlu4/Gqi5 and rmGlu4 GIRK, respectively. Valiglurax is a central nervous system (CNS) penetrant. Valiglurax can be used in research of Parkinson's disease[1].

Product Specifications

CAS Number

1976050-09-5

Product Name Alternative

VU0652957; VU2957

UNSPSC

12352005

Target

MGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/valiglurax.html

Purity

98.96

Solubility

DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

FC(C1=NC=CC2=C1C=CC(NC3=NNC4=NC=CC=C43)=C2)(F)F

Molecular Formula

C16H10F3N5

Molecular Weight

329.28

References & Citations

[1]Panarese JD, et, al. Discovery of VU2957 (Valiglurax) : An mGlu4 Positive Allosteric Modulator Evaluated as a Preclinical Candidate for the Treatment of Parkinson's Disease. ACS Med Chem Lett. 2018 Oct 16;10 (3) :255-260.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Elab Fluor® 700 Anti-Mouse CD31 Antibody[390]
E-AB-F1180M1-01 50 Tests

Elab Fluor® 700 Anti-Mouse CD31 Antibody[390]

Sign In for Pricing
View Details
Elab Fluor® 700 Anti-Mouse CD31 Antibody[390]
E-AB-F1180M1-02 100 Tests

Elab Fluor® 700 Anti-Mouse CD31 Antibody[390]

Sign In for Pricing
View Details
Elab Fluor® 700 Anti-Mouse CD31 Antibody[390]
E-AB-F1180M1-03 2x 100 Tests

Elab Fluor® 700 Anti-Mouse CD31 Antibody[390]

Sign In for Pricing
View Details
LRRC50 (DNAAF1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3F9]
TA504574BM 100 µL

LRRC50 (DNAAF1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI3F9]

Sign In for Pricing
View Details
Human TMEM132A activation kit by CRISPRa
GA110417 1 Kit

Human TMEM132A activation kit by CRISPRa

Sign In for Pricing
View Details
O,O-Diethyl Dithiophosphate Ammonium Salt
TRC-D444265-25MG 25 mg

O,O-Diethyl Dithiophosphate Ammonium Salt

Sign In for Pricing
View Details