Valiglurax
Valiglurax (VU0652957) is a potent, orally active and selective mGlu4 positive allosteric modulator with EC50 values of 64.6 nM and 197 nM for hmGlu4/Gqi5 and rmGlu4 GIRK, respectively. Valiglurax is a central nervous system (CNS) penetrant. Valiglurax can be used in research of Parkinson's disease[1].
Product Specifications
CAS Number
[1976050-09-5]
Product Name Alternative
VU0652957; VU2957
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/valiglurax.html
Purity
98.96
Solubility
DMSO : 83.33 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC(C1=NC=CC2=C1C=CC(NC3=NNC4=NC=CC=C43)=C2)(F)F
Molecular Formula
C16H10F3N5
Molecular Weight
329.28
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
SUMO-1 (GAP-modifying Protein 1, GMP1, OFC10, PIC1, SENP2, Sentrin 1, Small Ubiquitin-related Modifier 1, SMT3, SMT3 Suppressor of mif two 3 Homolog 1, SMT3C, SMT3H3, Ubiquitin Homology domain Protein PIC1, Ubiquitin Like 1, Ubiquitin like Protein UBL1) (
SUMO-1 (GAP-modifying Protein 1, GMP1, OFC10, PIC1, SENP2, Sentrin 1, Small Ubiquitin-related Modifier 1, SMT3, SMT3 Suppressor of mif two 3 Homolog 1, SMT3C, SMT3H3, Ubiquitin Homology domain Protein PIC1, Ubiquitin Like 1, Ubiquitin like Protein UBL1) (
Neurofibromin (NF1) (NM_001128147) Human Tagged ORF Clone Lentiviral Particle
