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USP8-IN-1

USP8-IN-1 is a USP8 inhibitor with an IC50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI50 of 82.04 μM (CN111138358A; U10) [1].

Product Specifications

CAS Number

2477650-96-5

UNSPSC

12352005

Target

Deubiquitinase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/usp8-in-1.html

Purity

99.07

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

[O-][N+](C1=CC=C(NC(N2CCN(CC2)C3=CC=C(C=C3N)OC)=S)C=C1)=O

Molecular Formula

C18H21N5O3S

Molecular Weight

387.46

References & Citations

[1]Zhiyu Li, et al. USP8 inhibitor and preparation method and application thereof. CN111138358A.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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