USP8-IN-1
USP8-IN-1 is a USP8 inhibitor with an IC50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI50 of 82.04 μM (CN111138358A; U10) [1].
Product Specifications
CAS Number
2477650-96-5
UNSPSC
12352005
Target
Deubiquitinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/usp8-in-1.html
Purity
99.07
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
[O-][N+](C1=CC=C(NC(N2CCN(CC2)C3=CC=C(C=C3N)OC)=S)C=C1)=O
Molecular Formula
C18H21N5O3S
Molecular Weight
387.46
References & Citations
[1]Zhiyu Li, et al. USP8 inhibitor and preparation method and application thereof. CN111138358A.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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