LVGRQLEEFL (mouse)

LVGRQLEEFL (mouse) can be named as G * peptide, corresponding to amino acids 113 to 122 in apolipoprotein J ([113,122] apoJ) }. LVGRQLEEFL (mouse) exhibits anti-inflammatory and anti-atherogenic properties. LVGRQLEEFL (mouse) can be added to an apoJ mimetic, to form HM-10/10 peptide, which is a mimetic peptide and a novel chimeric high density lipoprotein. HM-10/10 peptide protects retinal pigment epithelium (RPE) and photoreceptors from oxidant induced cell death[1][2].

Product Specifications

CAS Number

[608513-82-2]

UNSPSC

12352209

Target

Amino Acid Derivatives; Apolipoprotein

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lvgrqleefl-mouse.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](C(C)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N

Molecular Formula

C55H90N14O16

Molecular Weight

1203.39

References & Citations

[1]Su F, et al. A Novel HDL-Mimetic Peptide HM-10/10 Protects RPE and Photoreceptors in Murine Models of Retinal Degeneration. Int J Mol Sci. 2019 Sep 27;20 (19) :4807. |[2]Mishra VK, et al. Structure and lipid interactions of an anti-inflammatory and anti-atherogenic 10-residue class G (*) apolipoprotein J peptide using solution NMR. Biochim Biophys Acta. 2011 Jan;1808 (1) :498-507.