Galanin Receptor Ligand M35
Galanin Receptor Ligand M35 is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM) . Galanin Receptor Ligand M35 exerts a Ki values of 0.11 and 2.0 nM for human galanin receptor type 1 and 2, respectively[1][2].
Product Specifications
CAS Number
142846-71-7
UNSPSC
12352209
Target
Neuropeptide Y Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/galanin-receptor-ligand-m35.html
Purity
99.59
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(NCC(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(N4[C@@H](CCC4)C(NCC(N[C@H](C(N[C@@H](CO)C(N5[C@@H](CCC5)C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CC6=CC=CC=C6)=O)=O)=O)CC7=CC=CC=C7)=O)=O)=O)=O)=O)=O)=O)=O)NC(CNC([C@H](C)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@@H](NC(CN)=O)CC8=CNC9=CC=CC=C89)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C107H153N27O26
Molecular Weight
2233.60
References & Citations
[1]Kask K, et al. Binding and agonist/antagonist actions of M35, galanin (1-13) -bradykinin (2-9) amide chimeric peptide, in Rin m 5F insulinoma cells. Regul Pept. 1995 Nov 10;59 (3) :341-8.|[2]Webling KE, et al. Galanin receptors and ligands. Front Endocrinol (Lausanne) . 2012 Dec 7;3:146.|[3]Ogren SO, et al. Evidence for a role of the neuropeptide galanin in spatial learning. Neuroscience. 1992 Nov;51 (1) :1-5.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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