Anti-Mouse IL-3 Antibody (MP2-8F8)

Anti-Mouse IL-3 Antibody (MP2-8F8) is an anti-mouse IL-3 IgG1 monoclonal antibody. Anti-Mouse IL-3 Antibody (MP2-8F8) relieves joint inflammation by reducing synovial leukocyte infiltration and cytokine levels. Anti-Mouse IL-3 Antibody (MP2-8F8) can reduce the accumulation of basophils. Anti-Mouse IL-3 Antibody (MP2-8F8) can be used for researches on inflammation or infection conditions such as arthritis and parasitic infections[1][2][3].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Target

Interleukin Related; Parasite

Type

Inhibitory Antibodies

Related Pathways

Anti-infection; Immunology/Inflammation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-il-3-antibody-mp2-8f8.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Anti-MouseIL-3Antibody(MP2-8F8)]

Molecular Weight

(150 kDa)

References & Citations

[1]Brühl H, et al. Important role of interleukin-3 in the early phase of collagen-induced arthritis. Arthritis Rheum. 2009 May;60 (5) :1352-61.|[2]Drube S, et al. IL-3 is essential for ICOS-L stabilization on mast cells, and sustains the IL-33-induced RORγt+ Treg generation via enhanced IL-6 induction. Immunology. 2021 May;163 (1) :86-97.|[3]Min B, et al. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med. 2004 Aug 16;200 (4) :507-17.