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Aluminum phthalocyanine chloride

Aluminum phthalocyanine chloride is a photosensitizer that effectively inhibits the parasite Leishmania amazonensis (the causative agent of cutaneous leishmaniasis) by light-mediated cytolysis. Aluminum phthalocyanine chloride causes parasite morphology and cytolysis of isolated amasilians, while higher photosensitizer concentrations and light intensities are required to induce lysis of mammalian cells. Aluminum phthalocyanine chloride lyses parasites within infected J774 macrophages and can be used to further investigate the study of leishmaniasis[1].

Product Specifications

Product Name Alternative

AlClPc

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/aluminum-phthalocyanine-chloride.html

Smiles

[Cl-][Al+3]12([N](C(C3=CC=CC=C43)=N5)=C4N=C6C7=CC=CC=C87)[N-]6C8=NC9=[N]1C(C%10=CC=CC=C9%10)=NC%11=C(C=CC=C%12)C%12=C5[N-]2%11

Molecular Formula

C32H16AlClN8

Molecular Weight

574.96

Precautions

H302, H315, H319, H335

References & Citations

[1]Photodynamic sensitization of Leishmania amazonensis in both extracellular and intracellular stages with aluminum phthalocyanine chloride for photolysis in vitro

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-129959/Aluminum-phthalocyanine-chloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-129959/Aluminum-phthalocyanine-chloride-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

CAS Number

[14154-42-8]

Available Sizes

Curated Selection

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