Kisspeptin-10, human

Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression[1].

Product Specifications

CAS Number

[374675-21-5]

UNSPSC

12352209

Target

Kisspeptin Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Cancer-programmed cell death

Field of Research

Cancer; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Kisspeptin-10.html

Purity

99.68

Solubility

H2O : 10 mg/mL (ultrasonic)

Smiles

NC([C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC(CNC([C@H](CC2=CC=CC=C2)NC([C@H](CO)NC([C@H](CC(N)=O)NC([C@@H](NC([C@H](CC(N)=O)NC([C@@H](N)CC3=CC=C(C=C3)O)=O)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C63H83N17O14

Molecular Weight

1302.44

References & Citations

[1]Son HE, et al. Kisspeptin-10 (KP-10) stimulates osteoblast differentiation through GPR54-mediated regulation of BMP2 expression and activation. Sci Rep. 2018 Feb 1;8 (1) :2134.