Ceranib-2
Ceranib-2 is a potent and nonlipid ceramidase inhibitor that inhibits cellular ceramidase activity with an IC50 of 28 μM in SKOV3 cells. Ceranib-2 induces the accumulation of multiple ceramide species, decreases levels of sphingosine and sphingosine-1-phosphate (S1P), and induces cell apoptosis. Anticancer activity[1][2].
Product Specifications
CAS Number
1402830-75-4
Product Name Alternative
MCB-3837; DNV3846
UNSPSC
12352005
Hazard Statement
H302, H413
Target
Apoptosis; LPL Receptor
Type
Reference compound
Related Pathways
Apoptosis; GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ceranib-2.html
Concentration
10mM
Purity
98.92
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C1NC(C=CC=C2)=C2C(C3=CC=CC=C3)=C1C(/C=C/C4=CC=C(C=C4)OC)=O
Molecular Formula
C25H19NO3
Molecular Weight
381.42
Precautions
H302, H413
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Colloidal Gold Conjugated Sheep Affinity Purified Antibody to Mouse IgG1, 5nm
![Kallikrein 8 (KLK8) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A10]](https://cdn.genprice.uk/products/937/68dd1b71061270361ea1895e/imageurl/ta506131am.webp)
Kallikrein 8 (KLK8) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI1A10]
