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SARS-CoV-2 (COVID-19) S1 Protein, mFc Tag

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Product Specifications

Expression Region

Val 16 - Arg 685

Reactivity

Virus

Conjugation

Unconjugated

Tag

C-mFc (mIgG2a)

Field of Research

Infectious Disease & Virology

Endotoxin

1.0 EU per μg

Purity

90%

Form

Powder

Molecular Weight

101.9 kDa

Storage Conditions

-20°C

Notes

For research use only.

Applications Notes

This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 101.9 kDa. The protein migrates as 115-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

NCBI Accession Number

QHD43416.1

Preservative

PBS, pH 7.4

Available Sizes

Frequently Asked Questions

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