SARS-CoV-2 (COVID-19) S Protein RBD, mFc Tag
It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Product Specifications
Expression Region
Arg 319 - Phe 541
Reactivity
Virus
Conjugation
Unconjugated
Tag
C-mFc (mIgG2a)
Field of Research
Infectious Disease & Virology
Endotoxin
1.0 EU per μg
Purity
95%
Form
Powder
Molecular Weight
52.0 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 52.0 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
QHD43416.1
Preservative
PBS, pH 7.4
Available Sizes
Frequently Asked Questions
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