Bis-PEG9-acid
Bis- PEG9- acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis- PEG9- acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
Product Specifications
CAS Number
[1268488-70-5]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-peg9-acid.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Molecular Formula
C22H42O13
Molecular Weight
514.56
Precautions
H302, H315, H319, H335
References & Citations
[1]Bach A, et al. Design and synthesis of highly potent and plasma-stable dimeric inhibitors of the PSD-95-NMDAreceptor interaction. Angew Chem Int Ed Engl. 2009;48 (51) :9685-9.|[2]Norbert Basler, et al. Nucleoside-triphosphate conjugate and methods for the use thereof. WO2012150035A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers
Available Sizes
Curated Selection
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