Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Gp130/IL6ST, Human (HEK293, Fc)

Glycoprotein 130 (gp130) is a trans-membrane protein, is the common signal-transducing receptor subunit of the interleukin-6 (IL-6) family[1]. gp130 inhibits the cell growth and migration[3], decreases the STAT3 phosphorylation induced by IL-6, and decreases IL-6-induced increase of Ki67. gp130 shows anti-tumor, anti-inflammation and anti-nociceptive activity[4][5]. gp130/IL6ST Protein, Human (HEK293, Fc) is a recombinant protein with a Fc tag produced by HEK293 cells.

Product Specifications

Product Name Alternative

Gp130/IL6ST Protein, Human (HEK293, Fc), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/gp130-il6st-protein-human-hek293-fc.html

Purity

98.0

Molecular Formula

3572 (Gene_ID) P40189-1 (E23-I618) (Accession)

Molecular Weight

Approximately 97-130 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.

References & Citations

[1]Cao Y, et al. Glycoprotein 130 is associated with adverse postoperative clinical outcomes of patients with late-stage non-metastatic gastric cancer. Sci Rep. 2016 Dec 5;6:38364.|[2]Nogueira-Silva C, et al. The role of glycoprotein 130 family of cytokines in fetal rat lung development. PLoS One. 2013 Jun 24;8 (6) :e67607.|[3]Xu S, et al. gp130: a promising drug target for cancer therapy. Expert Opin Ther Targets. 2013 Nov;17 (11) :1303-28.|[4]Boettger MK, et al. Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis. Arthritis Res Ther. 2010;12 (4) :R140.|[5]Hong J, et al. Recombinant soluble gp130 protein reduces DEN-induced primary hepatocellular carcinoma in mice. Sci Rep. 2016 Apr 15;6:24397.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Storage Conditions

Stored at -20°C for 2 years

Scientific Category

Recombinant Proteins

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Human C4 binding protein, C4BP ELISA Kit
YLA1133HU-01 48 Tests

Human C4 binding protein, C4BP ELISA Kit

Sign In for Pricing
View Details
Human C4 binding protein, C4BP ELISA Kit
YLA1133HU-02 96 Tests

Human C4 binding protein, C4BP ELISA Kit

Sign In for Pricing
View Details
GPIIb/IIIa Recombinant Antibody [10E5] (OAAV00338)
OAAV00802-200UG 200 µg

GPIIb/IIIa Recombinant Antibody [10E5] (OAAV00338)

Sign In for Pricing
View Details
2-Chloro-3,5-dibromopyridine
OR8618-01 5 g

2-Chloro-3,5-dibromopyridine

Sign In for Pricing
View Details
2-Chloro-3,5-dibromopyridine
OR8618-02 25 g

2-Chloro-3,5-dibromopyridine

Sign In for Pricing
View Details
2-Chloro-3,5-dibromopyridine
OR8618-03 100 g

2-Chloro-3,5-dibromopyridine

Sign In for Pricing
View Details