Isodeoxyelephantopin

Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer[1][2].

Product Specifications

CAS Number

[38927-54-7]

UNSPSC

12352005

Target

Autophagy; NF-κB; Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Autophagy; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/isodeoxyelephantopin.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

C=C(C)C(O[C@@H](CC1=C2)[C@]3([H])[C@@](OC(C3=C)=O)([H])/C=C(C)/C[C@]2([H])OC1=O)=O

Molecular Formula

C19H20O6

Molecular Weight

344.36

References & Citations

[1]Verma SS, et al. Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer. Sci Rep. 2019 Nov 29;9 (1) :17980.|[2]Yunna Kim, et al. Treatment of Hominis placenta pharmacopuncture for a patient with mild neurocognitive disorder: Case report. J Pharmacopuncture. 2019 Dec; 22 (4) : 279–283.