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Dehydrobruceine A

Dehydrobruceine A is a low potent antitrypanosomal agent, with an IC50 of 88.5 nM for Plasmodium falciparum[1].

Product Specifications

CAS Number

73435-47-9

UNSPSC

12352005

Target

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/dehydrobruceine-a.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@]1([C@H]2O)[C@@]([C@H]3OC(CC(C)C)=O)([H])[C@@]([C@@](OC3=O)([H])CC4=C(C5=O)C)(CO1)[C@@]([C@H]2O)([H])[C@]4(C=C5O)C)OC

Molecular Formula

C26H32O11

Molecular Weight

520.53

References & Citations

[1]Saw Bawm, et al. In vitro antitrypanosomal activities of quassinoid compounds from the fruits of a medicinal plant, Brucea javanica. Vet Parasitol. 2008 Dec 20;158 (4) :288-94.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Plasmodium; Trypanosoma

Available Sizes

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