HIF-1 alpha (556-574)

HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. HIF-1 functions as master regulator of response to oxygen homeostasis[1].

Product Specifications

CAS Number

[1201633-99-9]

UNSPSC

12352209

Target

HIF/HIF Prolyl-Hydroxylase

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Purity

99.37

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(C[C@H]([2H])[C@@H]1[2H])C([C@H](C)NC([C@H](CC(C)C)NC([C@H](CCSC)NC([C@H](CCC(O)=O)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](N)CC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(N3[C@@H](CCC3)C(N[C@@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)CC(C)C)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C101H150D2N20O34S2

Molecular Weight

2256.54

References & Citations

[1]Ehrismann D, et al. Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay. Biochem J. 2007 Jan 1;401 (1) :227-34.