1-Naphthyl 3,5-dinitrobenzoate
1-Naphthyl 3,5-dinitrobenzoate is a potent 5-lipoxygenase inhibitor with IC50 values of 1.04 µM and 3.6 µM for 5-LOX and mPGES-1, respectively. 1-Naphthyl 3,5-dinitrobenzoate has strong inhibition activity in the human whole blood (HWB) assay with an IC50 value of 8.6 μM. 1-Naphthyl 3,5-dinitrobenzoate can be used in research of inflammation[1].
Product Specifications
CAS Number
[93261-39-3]
UNSPSC
12352005
Hazard Statement
H302+H312+H332
Target
Lipoxygenase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/1-naphthyl-3-5-dinitrobenzoate.html
Purity
99.49
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OC1=C2C=CC=CC2=CC=C1)C3=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C3
Molecular Formula
C17H10N2O6
Molecular Weight
338.27
Precautions
H302+H312+H332
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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