Acetyl-CoA synthetase

Acetyl-CoA synthetase (ACS) is a key enzyme that catalyzes the conversion of acetate to acetyl-CoA (Ac-CoA) . Acetyl-CoA synthetase catalyzes the formation of thioester bonds between coenzyme A and carboxylic acids, while simultaneously hydrolyzing ATP into AMP and pyrophosphate[1].

Product Specifications

CAS Number

[9012-31-1]

Product Name Alternative

ACS

UNSPSC

12352204

Target

Acetyl-CoA synthetase

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/acetyl-coa-synthetase.html

Solubility

10 mM in DMSO

Smiles

[Acetyl-CoAsynthetase]

References & Citations

[1]Sofeo N, et al. Altering the Substrate Specificity of Acetyl-CoA Synthetase by Rational Mutagenesis of the Carboxylate Binding Pocket. ACS Synth Biol. 2019 Jun 21;8 (6) :1325-1336.