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Nampt-IN-15

Nampt-IN-15 (Example 3) is an Nampt inhibitor. Nampt-IN-15 shows cytotoxicity against BxPC-3, HepG2, L540cy and MOLM-13, with IC50s of 38.5 nM, 8 nM, 8.5 nM, 7 nM respectively[1].

Product Specifications

CAS Number

2222981-61-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NAMPT

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nampt-in-15.html

Concentration

10mM

Purity

99.49

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(C1=CC(N)=CC=C1)N2CCC(CC2)CCCCNC(/C=C/C3=CN=CC=C3)=O

Molecular Formula

C24H30N4O2

Molecular Weight

406.52

Precautions

H302, H315, H319, H335

References & Citations

[1]Christopher Scott NEUMANN, et al. Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors. Patent. WO2018075600

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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