Human ASGR1 Protein, Fc Tag
ASGPR, a transmembrane C-type lectin, recognizes a wide variety of ligands that contain either terminal galactose (Gal) or N-acetylgalactosamine (Galc) residues and has been identified as a highly selective receptor on hepatocytes. The ASGR is composed of both a major (ASGR1) and minor subunit (ASGR2) . ASGR1 has been shown to be efficiently targeted to the plasma membrane and to undergo constitutive endocytosis and recycling and found mainly expressed in the human liver.
Product Specifications
UniProt
P07306
Expression Region
Gln 62 - Leu 291
Reactivity
Human
Conjugation
Unconjugated
Tag
N-Fc
Endotoxin
0.01 EU per μg
Purity
90%
Form
Powder
Molecular Weight
52.8 kDa
Storage Conditions
-20°C
Notes
For research use only.
Applications Notes
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 52.8 kDa. The protein migrates as 65-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Accession Number
P07306
Preservative
PBS, pH 7.4
Available Sizes
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