Glycyrrhizic acid (Standard)

Glycyrrhizic acid (Standard) is the analytical standard of Glycyrrhizic acid. This product is intended for research and analytical applications. Glycyrrhizic acid is a triterpenoid saponinl, acting as a direct HMGB1 antagonist, with anti-tumor, anti-diabetic activities.

Product Specifications

CAS Number

[1405-86-3]

Product Name Alternative

Glycyrrhizin (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Reference Standards; Virus Protease

Type

Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glycyrrhizic-acid-standard.html

Purity

97.54

Smiles

C[C@]12[C@@](C(C=C3[C@]2(CC[C@]4(C)[C@@]3([H])C[C@](C(O)=O)(C)CC4)C)=O)([H])[C@@]5([C@@](C(C)([C@@H](O[C@]6([H])[C@@H]([C@H]([C@H](O)[C@@H](C(O)=O)O6)O)O[C@]7([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]7O)C(O)=O)CC5)C)([H])CC1)C

Molecular Formula

C42H62O16

Molecular Weight

822.93

Precautions

H302, H315, H319, H335

References & Citations

[1]Su X, et al. Glycyrrhizic acid: A promising carrier material for anticancer therapy. Biomed Pharmacother. 2017 Sep 5;95:670-678|[2]Wang LY, et al. Glycyrrhizic acid increases glucagon like peptide-1 secretion via TGR5 activation in type 1-like diabetic rats. Biomed Pharmacother. 2017 Sep 4;95:599-604.|[3]Li C, et al. Glycyrrhizin, a Direct HMGB1 Antagonist, Ameliorates Inflammatory Infiltration in a Model of Autoimmune Thyroiditis via Inhibition of TLR2-HMGB1 Signaling. Thyroid. 2017 May;27 (5) :722-731.|[4]Xia Zhao, et al. A Simple Injectable Moldable Hydrogel Assembled from Natural Glycyrrhizic Acid with Inherent Antibacterial Activity. ACS Appl. Bio Mater. 2020, 3, 1, 648–653.