PI3Kδ/γ-IN-1
PI3Kδ/γ-IN-1 is a potent, selective PI3K-δ/γ inhibitor for research of hematological malignancies.
Product Specifications
CAS Number
1980884-01-2
UNSPSC
12352005
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pi3kδ-γ-in-1.html
Purity
99.85
Solubility
DMSO : ≥ 2.22 mg/mL
Smiles
O=C1N(C)C2=CN=C(NC3=CC=CC(S(=O)(N4CCC(O)CC4)=O)=C3)N=C2N(C)C5=CC=C(C)C=C15
Molecular Formula
C25H28N6O4S
Molecular Weight
508.59
References & Citations
[1]Ferguson FM, et al. Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-δ/γ Inhibitors. ACS Med Chem Lett. 2016 Aug 2;7 (10) :908-912.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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