PF 750
PF 750 is a selective and covalent fatty acid amide hydrolase (FAAH) inhibitor, with IC50s varied from 16.2-595 nM in different pre-incubation times. Covalently modifies the enzyme’s active site serine nucleophile[1].
Product Specifications
CAS Number
[959151-50-9]
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Autophagy; FAAH
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/PF_750.html
Purity
98.99
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=CC=C1)N(CC2)CCC2CC3=CN=C4C(C=CC=C4)=C3
Molecular Formula
C22H23N3O
Molecular Weight
345.44
Precautions
H315, H319, H320
References & Citations
[1]Ahn K, et al. Novel mechanistic class of fatty acid amide hydrolase inhibitors with remarkable selectivity. Biochemistry. 2007 Nov 13;46 (45) :13019-30.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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