KKL-10

KKL-10 is a small-molecule ribosome rescue inhibitor with broad-spectrum antimicrobial activity against bacteria.

Product Specifications

CAS Number

[952849-76-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/KKL-10.html

Purity

98.0

Solubility

DMSO : 2.78 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(Br)S1)NC2=NN=C(C3=CC=C(C)C=C3)O2

Molecular Formula

C14H10BrN3O2S

Molecular Weight

364.22

Precautions

H302, H315, H319

References & Citations

[1]Goralski TD, et al. Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication. Antimicrob Agents Chemother. 2016 May 23;60 (6) :3276-82.|[2]Tyler D P Goralski, et al. Inhibitors of Ribosome Rescue Arrest Growth of Francisella tularensis at All Stages of Intracellular Replication. Antimicrob Agents Chemother. 2016 May 23;60 (6) :3276-82.