PDE2/PDE10-IN-1
Product Specifications
UNSPSC Description
PDE2/PDE10-IN-1 is a phosphodiesterase 2 (PDE2) and PDE10 inhibitor with IC50s of 29 and 480 nM, respectively.
Target Antigen
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/PDE2-PDE10-IN-1.html
Purity
99.88
Solubility
DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
CC1=NC2=C(C=NC=C2)N3C1=NN=C3C4=CC=CC=C4Cl
Molecular Weight
295.73
References & Citations
[1]Rombouts FJ, et al. Pyrido[4,3-e][1,2,4]triazolo[4,3-a]pyrazines as Selective, Brain Penetrant Phosphodiesterase 2 (PDE2) Inhibitors. ACS Med Chem Lett. 2015 Jan 15;6(3):282-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-U00427/PDE2-PDE10-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-U00427/PDE2-PDE10-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1426833-08-0
Available Sizes
Curated Selection
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