ONO 207

ONO 207 (13,14-Dihydrodinoprost) is the analog of PGF2α which has no unsaturation in the lower side chain. It causes luteolysis in hamsters with a potency five times higher than PGF2α. The ED50 value for 13,14-dihydro PGF2α as a luteolytic agent in hamsters is 1.5 μg/100 g.

Product Specifications

CAS Number

[27376-74-5]

Product Name Alternative

13,14-Dihydrodinoprost; 13,14-dihydro PGF2α

UNSPSC

12352211

Hazard Statement

H225-H319-H336-H360

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/ono-207.html

Smiles

O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)CC[C@H](CCCCC)O)C/C=C\CCCC(O)=O

Molecular Formula

C20H36O5

Molecular Weight

356.50

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501

References & Citations

[1]Andersen, et al. Molecular basis for prostaglandin potency. III. Tests of the significance of the 'hairpin conformation' in biorecognition phenomena. Prostaglandins 22, 841-856 (1981) .