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Boc-HyNic-PEG2-DBCO

Product Specifications

UNSPSC Description

Boc-HyNic-PEG2-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-HyNic-PEG2-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/boc-hynic-peg2-dbco.html

Smiles

O=C(NCCOCCOCCC(NCCC(N1C(C=CC=C2)=C2C#CC(C=CC=C3)=C3C1)=O)=O)C4=CN=C(NNC(OC(C)(C)C)=O)C=C4

Molecular Weight

670.75

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-133502/Boc-HyNic-PEG2-DBCO-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-133502/

Available Sizes

Curated Selection

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