Propargite

Propargite is a pesticide used to kill mites. Propargite induces β-cell necrosis preceded by DNA damage. Propargite induces MIN6 cell death with an IC50 of 1 μM[1]. Propargite is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[2312-35-8]

UNSPSC

12352005

Hazard Statement

H227-H315-H318-H330-H351-H410

Target

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/propargite.html

Solubility

10 mM in DMSO

Smiles

O=S(OCC#C)OC1C(OC2=CC=C(C(C)(C)C)C=C2)CCCC1

Molecular Formula

C19H26O4S

Molecular Weight

350.47

Precautions

P210-P260-P264-P271-P273-P280-P284-P302+P352-P304+P340-P305+P351+P338-P362+P364-P370+P378-P391-P403-P403+P233-P405-P501

References & Citations

[1]Ting Zhou, et al. A hPSC-based Platform to Discover Gene-Environment Interactions That Impact Human β-cell and Dopamine Neuron Survival. Nat Commun. 2018 Nov 16;9 (1) :4815.