JS11
Product Specifications
UNSPSC Description
JS11 is an inhibitor for natriuretic polypeptide receptor 1 (Npr1) with an IC50 of 1.9 μM for hNpr1. JS11 ameliorates the pruritus in mouse models[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/js11.html
Solubility
DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(C1=CC=C2C(N(CC3CC3)C(N2C4CCCCC4)=O)=C1)NCC5=CC(C)=NO5
Molecular Weight
408.49
References & Citations
[1]Hoon MA, et al., Compositions and methods for the inhibition of pruritus. WO2019090039.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-153650/JS11-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-153650/JS11-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1394592-04-1
Available Sizes
Curated Selection
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