N-Nitrosodibenzylamine-d4
N-Nitrosodibenzylamine-d4 is deuterium labeled N-Nitrosodibenzylamine. N-Nitrosodibenzylamine is a potent and orally activity DNA damage inducer. N-Nitrosodibenzylamine induces DNA single-strand breaks (SSBs) [1][2].
Product Specifications
CAS Number
20002-23-7
UNSPSC
12352005
Target
DNA/RNA Synthesis; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Smiles
[2H]C(C1=CC=CC=C1)([2H])N(N=O)C([2H])([2H])C2=CC=CC=C2
Molecular Formula
C14H10D4N2O
Molecular Weight
230.30
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Appel KE, et al. DNA damage induced by N-nitrosodibenzylamine and N-nitroso-alpha-acetoxybenzyl-benzylamine in mammalian cell systems and in vivo. Toxicol Lett. 1990 Aug;52 (3) :269-77.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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