PKR activator 4
PKR activator 4 (example 7A) is a potent pyruvate kinase R (PKR) activator. PKR activator 4 has the potential for the research of blood disorders[1].
Product Specifications
CAS Number
[2283420-05-1]
UNSPSC
12352005
Target
Pyruvate Kinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/pkr-activator-4.html
Purity
96.72
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1NN=CC2=C1N(C)C3=C2SC(CC4=NN(COCC[Si](C)(C)C)C=C4)=N3
Molecular Formula
C18H24N6O2SSi
Molecular Weight
416.57
References & Citations
[1]Giovanni Cianchetta et al. Pyruvate kinase activators for use in treating blood disorders. WO2019035864A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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