PKR activator 4

PKR activator 4 (example 7A) is a potent pyruvate kinase R (PKR) activator. PKR activator 4 has the potential for the research of blood disorders[1].

Product Specifications

CAS Number

[2283420-05-1]

UNSPSC

12352005

Target

Pyruvate Kinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/pkr-activator-4.html

Purity

96.72

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1NN=CC2=C1N(C)C3=C2SC(CC4=NN(COCC[Si](C)(C)C)C=C4)=N3

Molecular Formula

C18H24N6O2SSi

Molecular Weight

416.57

References & Citations

[1]Giovanni Cianchetta et al. Pyruvate kinase activators for use in treating blood disorders. WO2019035864A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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