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Cyclo (L-Leu-L-Pro)

Cyclo (L-Leu-L-Pro) is an inhibitory substance targeting to production of norsolorinic acid (NA, a precursor of aflatoxin), which can be isolated from A. xylosoxidans NFRI-A1. Cyclo (L-Leu-L-Pro) inhibits accumulation of NA by A. parasiticus NFRI-95 and inhibits spore formation. Cyclo (L-Leu-L-Pro) inhibits aflatoxin production with an IC50 of 0.2 mg/mL in A. parasiticus SYS-4[1].

Product Specifications

CAS Number

[2873-36-1]

Product Name Alternative

Cyclo (L-prolyl-L-leucyl)

UNSPSC

12352209

Hazard Statement

H302, H317

Target

Fungal

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cyclo-l-leu-l-pro.html

Purity

99.84

Solubility

DMSO : 100 mg/mL

Smiles

O=C(N1[C@]([H])2CCC1)[C@@H](NC2=O)CC(C)C

Molecular Formula

C11H18N2O2

Molecular Weight

210.27

Precautions

H302, H317

References & Citations

[1]Yan PS, et al. Cyclo (L-leucyl-L-prolyl) produced by Achromobacter xylosoxidans inhibits aflatoxin production by Aspergillus parasiticus. Appl Environ Microbiol. 2004 Dec;70 (12) :7466-73.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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