MQAE

MQAE is a chloride ion (Cl-) fluorescent probe that can be used to measure chloride concentrations. The fluorescence intensity of MQAE decreases proportionally as Cl- ions increase. MQAE has high cell permeability and is suitable for fluorescence detection such as confocal microscopy and flow cytometry (Ex/Em=350/460 nm) [1][2].

Product Specifications

CAS Number

[162558-52-3]

UNSPSC

12171500

Hazard Statement

H302, H315, H319, H335

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/MQAE.html

Purity

99.84

Solubility

DMSO : ≥ 35 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

COC1=CC2=CC=C[N+](CC(OCC)=O)=C2C=C1.[Br-]

Molecular Formula

C14H16BrNO3

Molecular Weight

326.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Andersson C, et al. Determination of chloride efflux by X-ray microanalysis versus MQAE-fluorescence. Microsc Res Tech. 2|[2]Koncz C, et al. Use of MQAE for measurement of intracellular [Cl-] in cultured aortic smooth muscle cells. Am J Physiol. 1994 Dec;267 (6 Pt 2) :H2114-23.|[3]Kovalchuk Y, et al. Two-photon chloride imaging using MQAE in vitro and in vivo. Cold Spring Harb Protoc. 2012 Jul 1;2012 (7) :778-85.