(-) -Pinoresinol
(-) -Pinoresinol is a plant-derived tetrahydrofuran lignan that inhibits α-glucosidase and acts as a hypoglycemic agent. (-) -Pinoresinol has some anti-inflammatory effects and acts as a chemopreventive agent, inducing increased apoptosis and cell cycle G2/M arrest[1].
Product Specifications
CAS Number
[81446-29-9]
UNSPSC
12352005
Target
Apoptosis; Glycosidase
Type
Natural Products
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/minus-pinoresinol.html
Purity
99.83
Solubility
10 mM in DMSO
Smiles
OC1=CC=C([C@@H]2OC[C@]3([H])[C@@]2([H])CO[C@H]3C4=CC=C(O)C(OC)=C4)C=C1OC
Molecular Formula
C20H22O6
Molecular Weight
358.39
References & Citations
[1]Lucia Fini, et al. Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM-p53 cascade in colon cancer cell lines. Carcinogenesis. 2008 Jan;29 (1) :139-46.|[2]Alexandrine During, et al. Among plant lignans, pinoresinol has the strongest antiinflammatory properties in human intestinal Caco-2 cells. J Nutr. 2012 Oct;142 (10) :1798-805.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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