Peficitinib
Peficitinib (ASP015K) is an orally active JAK inhibitor, with IC50s of 3.9, 5.0, 0.7 and 4.8 nM for JAK1, JAK2, JAK3 and Tyk2, respectively[1].
Product Specifications
CAS Number
944118-01-8
Product Name Alternative
ASP015K; JNJ-54781532
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Peficitinib.html
Purity
99.43
Solubility
DMSO : 58.33 mg/mL (ultrasonic)
Smiles
O[C@](C[C@@H]1C[C@H]2C3)(C2)C[C@@H]3[C@H]1NC4=C5C(NC=C5)=NC=C4C(N)=O
Molecular Formula
C18H22N4O2
Molecular Weight
326.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Ito M, et al. A novel JAK inhibitor, peficitinib, demonstrates potent efficacy in a rat adjuvant-induced arthritis model. J Pharmacol Sci. 2017 Jan;133 (1) :25-33.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
JAK1; JAK2; JAK3; Tyk2
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Cullin 3 Recombinant Rabbit Monoclonal Antibody [JE57-80]](https://cdn.genprice.uk/products/992/68dd1c90061270361ea8298f/imageurl/ha721882.webp)
HA721882 100 µL
Cullin 3 Recombinant Rabbit Monoclonal Antibody [JE57-80]
Sign In for Pricing
View Details 
BNC883261-100 1x 100 µL
Lymphocyte Activation Gene 3 (LAG-3) (Negative Checkpoint Regulator) (LAG3/3261), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
LC424914 20 µg
XPG (ERCC5) (NM_000123) Human Over-expression Lysate
Sign In for Pricing
View Details 
PKSH031335 20 µg
Recombinant Human Prostatic Acid Phosphatase/ACPP Protein (His Tag)
Sign In for Pricing
View Details