Purified Anti-Human CD7 Antibody[HIT7]
Product Specifications
Background
CD7 is a 40 kD type I transmembrane glycoprotein also known as gp40. It is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly) . CD7 is also expressed on acute lymphocytic leukemia (ALL) and some acute myeloid leukemia (AML) cells. CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 costimulation can induce cytokine secretion and modulate cellular adhesion.
Abbreviation
CD7
Gene ID
924
UniProt
P09564
Host
Mouse
Reactivity
Human
Target
CD7; GP40; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; TP41
Clonality
Monoclonal
Clone
HIT7
Conjugation
Unconjugated
Applications
FCM
Field of Research
Costimulatory Molecules; Immunology
Concentration
≥ 1 mg/mL
Dilution
66
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
Shipping Conditions
Ice bag
Storage Conditions
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Recommended Usage
6
Isotype
Mouse IgG1, κ
Available Sizes
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