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HSPA5 antibody

Product Specifications

Background

GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER) .It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth.

Synonyms

Endoplasmic reticulum chaperone BiP|78 kDa glucose-regulated protein (GRP-78) |Binding-immunoglobulin protein (BiP) |Heat shock protein 70 family protein 5 (HSP70 family protein 5) |Heat shock protein family A member 5|Immunoglobulin heavy chain-binding protein|HSPA5|GRP78

UniProt

P11021

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

Endoplasmic reticulum chaperone BiP

Target

HSPA5

Clonality

Monoclonal

Isotype

IgG1

Applications

ELISA, WB, IHC, IF

Purification

Protein A+G purification

Dilution

WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

70-78 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

3F8

Tested Applications

ELISA, WB, IHC, IF

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