HSPA5 antibody
Product Specifications
Background
GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER) .It is a constitutively expressed resident protein of the ER in all eukaryotic cells. Recently it has been reported that GRP78 is associated with apoptosis or inhibition of cancer cell growth.
Synonyms
Endoplasmic reticulum chaperone BiP|78 kDa glucose-regulated protein (GRP-78) |Binding-immunoglobulin protein (BiP) |Heat shock protein 70 family protein 5 (HSP70 family protein 5) |Heat shock protein family A member 5|Immunoglobulin heavy chain-binding protein|HSPA5|GRP78
UniProt
P11021
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Endoplasmic reticulum chaperone BiP
Target
HSPA5
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC, IF
Purification
Protein A+G purification
Dilution
WB: 1:2000-1:20000; IHC: 1:50-1:200; IF: 1:50-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
70-78 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
3F8
Tested Applications
ELISA, WB, IHC, IF
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