Ziftomenib
Ziftomenib (KO-539) is an orally active menin-MLL interaction inhibitor with antitumor activities (WO2017161028A1, compound 151) [1].
Product Specifications
CAS Number
2134675-36-6
Product Name Alternative
KO-539
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ziftomenib.html
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)(F)F)S6)C6=NC(NC)=N5)CC4)=C3C
Molecular Formula
C33H42F3N9O2S2
Molecular Weight
717.87
References & Citations
[1]Tao Wu, et al. Substituted inhibitors of menin-mll and methods of use. WO2017161028A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
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