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Ziftomenib

Ziftomenib (KO-539) is an orally active menin-MLL interaction inhibitor with antitumor activities (WO2017161028A1, compound 151) [1].

Product Specifications

CAS Number

2134675-36-6

Product Name Alternative

KO-539

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ziftomenib.html

Purity

99.67

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)(F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Molecular Formula

C33H42F3N9O2S2

Molecular Weight

717.87

References & Citations

[1]Tao Wu, et al. Substituted inhibitors of menin-mll and methods of use. WO2017161028A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Frequently Asked Questions

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