Famotidine
Famotidine (MK-208) is a competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
Product Specifications
CAS Number
76824-35-6
Product Name Alternative
MK-208
UNSPSC
12352005
Hazard Statement
H303, H315, H319, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Endocrinology; Cancer; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Famotidine.html
Purity
99.85
Solubility
DMSO : ≥ 100 mg/mL|H2O : < 0.1 mg/mL
Smiles
N=C(NS(=O)(N)=O)CCSCC1=CSC(NC(N)=N)=N1
Molecular Formula
C8H15N7O2S3
Molecular Weight
337.45
Precautions
H303, H315, H319, H335
References & Citations
[1]Inan, A., et al., Effects of the histamine H2 receptor antagonist famotidine on the healing of colonic anastomosis in rats. Clinics (Sao Paulo), 2009. 64 (6) : p. 567-70.|[2]Miyata, K., et al., Studies on the mechanism for the gastric mucosal protection by famotidine in rats. Jpn J Pharmacol, 1991. 55 (2) : p. 211-22.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H2 Receptor
Available Sizes
Frequently Asked Questions
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